ABSTRACT NUMBER - S2008

ALCON ACRYSOF IOL GLISTENINGS: IS THE CHROMOPHORE THE CULPRIT?


Philip House1, Anmar Abdul-Rahman2, Josephine Richards3, Blasco D’Souza4

Meeting:  2018 RANZCO


Purpose: Patients with Alcon Acrysof IOLs were audited for glistenings density to determine whether glistenings were more common in different lens models or in lens with or without the yellow chromophore.
Method: Patients from two private practices were assessed using the criteria established by Werner (Glistenings and surface light scattering in intraocu- lar lenses, Liliana Werner, JCRS 2010; 36:1398– 1420). All patients seen as routine follow ups, who had at least one Acrysof IOL in situ for more than 12 months, were prospectively included yielding a study group of 301 eyes of 178 patients. There were
17 three piece IOLs, 74 SA60AT, 57 SN60AT, 139 SN60WF and 14 SN6AT × toric lenses.
Results: The clear IOLs had been in situ longer than the yellow lenses: Clear (N = 91 Mean 17, Median
7 years). Yellow (N = 204 Mean 5.5, Median
4.5 years)
Glistenings densities on the Werner scale were: Clear (Mean 0.4, Median 0), Yellow (Mean 1.2, Median 1). To address the unequal time in situ, three groups, with similar times in situ, were selected for further analysis (74 SA60AT, 57 SN60AT, 74 SN60WF)
using Chi-squared (χ2) test on lens chromopore tab-
ulated against glistening grade. Yellow lenses showed more glistenings than clears (χ2 = 44.69, P < 0.0005), while SN60AT and SN60WF were not sig- nificantly different on Wilcoxon Rank Sum and Mann Whitney Tests, but the SA60ATs were signifi- cantly different from both (P < 0.0005) Conclusion: Glistenings are more common in Acry- sof IOLs containing the yellow chromophore than in clear lenses.

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