ABSTRACT NUMBER - S0506

AVASCULAR RETINA – IS THIS THE NEW RETINOPATHY OF PREMATURITY?


Sigal Zmujak Yehiam, Samantha Simkin, Rasha Al-Taie, Shuan Dai

Meeting:  2018 RANZCO


Purpose: In New Zealand the rate of retinopathy of prematurity (ROP) treatment is decreasing, however there has been increasing anecdotal observation of per- sistent avascular retina in this cohort. Persistent avascu- lar retina may increase the risk of retinal detachment in infants screened for ROP. Changes in neonatal care including higher oxygen saturation (SpO2) targets may be attributable. This study aims to determine the prevalence of avascular retina and the association of SpO2 targets in children screened for ROP.
Methods: Retrospective review of RetCam images from ROP screening of infants born in Auckland between 2013 and 2017, were assessed for avascular retina. Infants born in 2015 were excluded due to SpO2 being changed from low (88-92%) to high (90-94%) in this year. Infants were divided into two groups: low SpO2 (2013-2014), high SpO2 (2016-2017) for comparison.
Results: A total of 487 infants were included (248 in the low SpO2 group and 239 in the high SpO2), avas- cular retina was present in 62 infants (12.7%). Infants exposed to low SpO2 had significantly more cases of avascular retina than those receiving high SpO2 (39 and 23 infants respectively; P = 0.043). There was no significant difference in birth weight, gestational age, or severity of ROP between the two groups.
Conclusions: Persistent avascular retina is present in over 12% of infants who are screened for ROP but who do not receive treatment. The higher SpO2 target did not correlate with an increased incidence of avascular retina. Further research into associated risk factors and long-term outcomes is needed.

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