Sophia Zagora1 2, Richard Symes1,2, Aaron Yeung1 ,2, Will Yates1,2, Denis Wakefield3, Peter McCluskey1,2

Purpose: To report the pattern of uveitis in patients attending a tertiary uveitis service in Sydney, Australia

Methods: The charts of patients seen between January 2009 and December 2015 were retrospectively reviewed. Data pertaining to patient demographics, eye examination on presentation, workup and final diagnoses were collected.

Results: The total number of patients with uveitis seen over this period was 1165. There were 650 males (56%) and 515 females (44%). There were 838 patients aged 17-60 years (72%) and 327 patients aged more than 60 years (28%). Uveitis was anterior in 735 patients (63%), posterior in 234 patients (20%), pan in 109 patients (9%) and intermediate in 87 patients (8%). The most common noninfectious etiologies were HLA B27+ve (264 patients; 23%), Sarcoidosis (78 patients; 7%) and Fuchs (33 patients; 3 %), whilst VZV (51 patients; 4%), HSV (49 patients; 4%), Tuberculosis (47 patients; 4%) and Toxoplasmosis (47 patients; 4%) were the most common infectious causes of inflammatory eye disease. No identifiable association was found in 368 patients (32%). HLA B27 was more prevalent in the younger age group compared to the older age group (p<0.001, Chi squared test), but there was no difference between the age groups for no identifiable cause (p value 0.24) and Sarcoidosis (p value 0.08).

Conclusions: This retrospective case review reveals a broad spectrum of uveitis in a tertiary referral service in Sydney, Australia. It is comparable to other major studies around the world.