David Holmes, Michelle Hui, Colin Clement

Purpose: To compare the outcome of early verses delayed Nd:YAG laser goniopuncture (LGP) after deep sclerectomy (DS) for open-angle glau- coma (OAG).
Methods: A retrospective study of consecutive OAG eyes that underwent an LGP following DS were recruited between June 2012 to November 2015. Success was defined as intraocular pressure (IOP) less than 21, 18 and 15 mmHg and a reduction of more than 20% IOP from baseline with medications (qualified success) or without medications (complete success).
Results: 102 eyes with OAG that underwent DS were recruited into the study. Of these, 49 (47.6%) eyes had undergone LGP post DS. The probability of qualified success at 60 months for all LGP eyes with IOP less than 21, 18 and 15 mmHg was 70.5%,
62.3 and 35.3%, respectively. When eyes that had early LGP post DS (<3 months, n = 22) were com- pared to eyes with delayed LGP post DS (3 3 months, n = 27), there were no significant differences found for each of the defined levels of success (P > 0.05). There was no significant difference in complications between early and delayed LGP groups. Conclusion: There appears to be no difference in the efficacy and safety of LGP performed early com- pared to delayed after DS. This study corroborates previous published data confirming LGP is an effec- tive and safe procedure for lowering IOP post DS procedure.